Obesity – science, food and waistlines and Otto Wolff Lecture
In the UK, and globally, we face an epidemic of obesity with huge implications for society and our healthcare systems. Obesity is not just a health problem in adults, it impacts children as well. Furthermore, the origins of adult obesity begin in childhood and adolescence. Recent research has helped us to understand how we become hungry and why some people eat too much.
This resource page provides useful information on the endocrine, neural and psychological bases of obesity as well as the genetic factors that contribute to its development. That knowledge now has relevance to the clinical management of obesity.
Material on this resources page gives a sound background on:
- The pathogenesis of obesity
- Valuable insights into the behavioural aspect of the development of obesity in children
- The impact of exercise and life style changes on modification of obesity
- Drug therapy and surgery as important modalities of treatment
Professor Russell Viner, Professor in Adolescent Health, UCL Institute of Child Health.Date: 17th January 2017
Professor Gareth Leng, Professor of Experimental Physiology, University of Edinburgh.Date: 17th January 2017
Dr Tony Goldstone, Senior Clinical Research Fellow, Imperial College London.Date: 17th January 2017
Professor Paul Gately, Professor of Exercise and Obesity, Leeds Beckett University.Date: 17th January 2017
Dr Clare Llewellyn, Lecturer in Behavioural Obesity Research, University College London.
Date: 17th January 2017
Mr Sanjay Purkayastha, Consultant Surgeon, Imperial College London.Date: 17th January 2017
interviews and other videos
Mr Sanjay Purkayastha, Consultant Surgeon, Imperial College London.Date: 20th February 2017
Professor Paul Gately, Professor of Exercise and Obesity, Leeds Beckett University.Date: 20th February 2017
Professor John Wilding, Professor of Medicine and Honorary Consultant Physician, Obesity and Endocrinology Research Theme Lead for Metabolism and Nutrition Institute of Ageing and Chronic Disease Clinical Sciences Centre, Aintree University Hospital.Date: 20th February 2017
Professor Sadaf Farooqi, Wellcome Trust Senior Clinical Fellow and Professor of Metabolism and Medicine, University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital.Date: 20th February 2017
All the references listed below are available in the RSM Library collection and can be accessed via the RSM’s e-resources area.
- Bray, G. A., Frübeck, G., Ryan, D. H., and Wilding, J. P. H. (2016). Management of obesity. The Lancet. 387 (10031), pp. 1947-56.
- Farooqi, S. I. (2015). Genetic, molecular and physiological mechanisms involved in human obesity: Society for Endocrinology Medal Lecture 2012. Clinical Endocrinology. 82 (1), pp. 23-8.
- Llewellyn, C. H., Trzaskowski, M., Van Jaarsveld, C. H., Plomin, R., and Wardle, J. (2014). Satiety mechanisms in genetic risk of obesity. JAMA Pediatrics. 168 (4), pp. 338-44.
- Llewellyn, C. and Wardle, J. (2015). Behavioral susceptibility to obesity: Gene-environment interplay in the development of weight. Physiology & Behavior. 152 (Pt B), pp. 494-501.
- Scholtz, S., Goldstone, A. P., and Le Roux, C. W. (2015). Changes in reward after gastric bypass: the advantages and disadvantages. Current Atherosclerosis Reports. 17 (10), pp. 61.
- Ziauddeen, H., Farooqi, I. S., and Fletcher, P. C. (2012). Obesity and the brain: How convincing is the addiction model? Nature Reviews Neuroscience. 13 (4), pp. 279-286.
The following references are not available in the RSM Library; however they can be accessed online via external websites.
- Colquitt, J. L., Pickett, K., Loveman, E., and Frampton, G. K. (2014). Surgery for weight loss in adults. The Cochrane database of systematic reviews, (8), pp. CD003641. Online at http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003641.pub4/full
- Department of Health, Prime Minister’s Office, Cabinet Office and Treasury, (2016). Childhood obesity; a plan for action. London: HM Government. Online at https://www.gov.uk/government/publications/childhood-obesity-a-plan-for-action
- Ells, L. J., Mead, E., Atkinson, G., Corpeleijn, E., Roberts, K., Viner, R., Baur, L., Metzendorf, M., and Richter, B. (2015). Surgery for the treatment of obesity in children and adolescents. The Cochrane database of systematic reviews. (6), pp. CD011740. Online at http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011740/full
- Sabatier, N., Leng, G., and Menzies, J. (2013). Oxytocin, feeding, and satiety. Frontiers in Endocrinology, 4, pp. 35. Online at the Edinburgh Research Explorer, The University of Edinburgh: http://www.research.ed.ac.uk/portal/files/8309412/Oxytocin_feeding_and_satiety.pdf